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CX2SA  > SCIENC   21.03.06 04:29l 90 Lines 5122 Bytes #999 (0) @ WW
BID : 45779_CX2SA
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Subj: Search for alien life...
Path: DB0FHN<DB0FOR<DB0SIF<DB0EA<DB0RES<DK0WUE<I0TVL<CX2SA
Sent: 060321/0156Z @:CX2SA.LAV.URY.SA #:45779 [Minas] FBB7.00e $:45779_CX2SA
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             Search for alien life challenges current concepts
             =================================================

For scientists  eying distant  planets and  solar systems  for signs  of alien
activity, University of Colorado  at Boulder Professor Carol  Cleland suggests
the first order of business is to keep an open mind.

It may be a mistake to try to define life, given such definitions are based on
a single example --  life on Earth, said  Cleland, a philosophy professor  and
fellow  at  the  NASA-funded  CU-Boulder  Center  for  Astrobiology.  The best
strategy is  probably to  develop a  "general theory  of living  systems," she
said.

Many  biologists agree  the best  definition of  living systems  today is  the
"chemical  Darwinian  definition" involving  self-sustaining  chemical systems
that undergo evolution  at the molecular  level, she said.  But the theory  is
limited in  that life  on Earth  probably resulted  from physical and chemical
"contingencies" present at the time of its origin on the planet.

"What we really need  to do is to  search for physical systems  that challenge
our current  concept of  life, systems  that both  resemble familiar  life and
differ from  it in  provocative ways,"  she said.  Cleland participated  in an
astrobiology symposium at the annual American Association for the  Advancement
of Science meeting held in St. Louis Feb. 16 to Feb. 20.

In 1976, for example, NASA's  Viking 1 spacecraft conducted automated  biology
experiments  on  Mars  by  mixing  soil  samples  with  radioactively  labeled
nutrients to  determine if  metabolic "burps"  from possible  extraterrestrial
microbes could be detected, she said. Although positive readings convinced  at
least some team scientists that  life was present, a subsequent  investigation
by a second Viking instrument failed to find evidence of organic molecules  on
the planet's surface.

"Initially,  the  scientists were  ready  to break  out  the champagne,"  said
Cleland. "But because subsequent investigations yielded baffling results  that
didn't fit the original metabolic  definition of life they were  working with,
NASA eventually concluded the original  signal was not evidence of  life. This
is an experiment that is still debated today, and it's a classic example of an
anomaly."

Although there  are more  than 100  combinations of  nucleic acids  in nature,
terrestrial life constructs all  of its proteins from  only about 20 of  them,
suggesting  a  single origin  for  life on  Earth,  said Cleland.  "It's  very
difficult to generalize about life based on just one example," she said.

An article  by Cleland  and CU-Boulder  molecular, cellular  and developmental
biology  Professor   Shelley  Copley,   published  online   in  the   Jan.  16
International Journal of Astrobiology, explores the idea that an  "alternative
microbial life" may  exist on Earth.  Such a "shadow  biosphere" could have  a
different molecular architecture and biochemistry than known life and would be
undetectable with  current techniques  like microscopy,  cell cultivation  and
Polymerase Chain Reaction amplification, the authors wrote.

Despite new suites of sophisticated instruments developed in recent years, the
ability of scientists  to detect life  on Mars or  in another solar  system is
probably very limited, Cleland said. "If the DNA in an alien organism was even
slightly different than the  DNA in life on  Earth, with a different  suite of
nucleotide bases to encode genetic  information, we probably wouldn't be  able
to recognize it. "

So what  might be  out there?  "It's not  too far-fetched  to imagine an alien
microbe whose genetic material directly and adaptively changes in response  to
different environmental  conditions," said  Cleland. "Instead  of looking  for
life as we  know it, scientists  may be better  served to look  for anomalies,
which amounts to looking for life as we don't know it."

In  the past  decade, scientists  have discovered  more than  170 new  planets
around other stars, a number that seems to grow by the month due to clever new
planet-hunting  techniques,  Cleland  said.  In  the  future,  astrobiologists
surveying other planets  will no doubt  encounter non-living systems  that are
"really weird," she said.

"In such cases, it probably is best to suspend judgment," she said. "The great
strength of science is its tentativeness, and through history, it has been the
careful  analysis  of  anomalies  that  have  eventually  changed   scientific
paradigms."

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